Last Updated on December 7, 2020
- The San Francisco 49ers are -1 against the Buffalo Bills on Monday Night Football. The total is set to 47 points.
- The Bills have hit the over in eight of 11 games this season.
- The 49ers rank top 10 in the NFL in yards per carry (4.0) and yards per game (108.7).
- Buffalo is on track to win their first AFC East title in 25 years.
The San Francisco 49ers (5-6) are looking to move to 3-1 over AFC East foes this season when they play the Buffalo Bills (8-3) on Monday Night Football. This Week 13 matchup features two teams who aren’t quite considered among the top Super Bowl contenders, but they are both fighting for playoff positioning.
The Bills have a solid grasp on the AFC East heading into Monday, but the Miami Dolphins are still within striking distance. With a win, the 49ers will move to 6-6 on the year and could put them in a position to snag a Wild Card spot.
The Action Rush Monday Night Football betting guide has the best odds, interesting props, analysis, and everything else you need to know for 49ers vs. Bills in Week 13.
49ers – Bills Odds MNF Week 13[metabet_core_game_tile query=”nfl/bills” site_id=”actionrush”]
The San Francisco 49ers are modest one-point favorites over the Buffalo Bills this week, but bettors can grab Buffalo at +1.5 on some sportsbooks. The Niners are -106 on the moneyline while the Bills are -102. There is decent value on the moneyline there for anyone interested in staying away from the spread. The total is set to 47 points.
Both the 49ers and the Bills have been fairly even against the spread this season. The Bills are 6-5 ATS while the Niners are 5-6 on DraftKings Sportsbook. However, Buffalo has hit the over on eight of 11 games this year.
Public Betting Picks at DraftKings
MONDAY NIGHT FOOTBALL BETTING SPLITS
|Teams||Point Spread||% Handle||% Bets||Total Points||% Handle||% Bets||Moneyline||% Handle||% Bets|
|WAS Football Team||+6.5||17%||22%||Over 44.0||65%||68%%||+230||11%||11%|
|PIT Steelers||-6.5||83%||78%||Under 44.0||35%||32%||-286||89%||89%|
|BUF Bills||-1||75%||76%||Over 47.0||75%||72%||-107||79%||76%|
|SF 49ers||+1||25%||24%||Under 47.0||25%||28%||-107||21%||24%|
Bills vs. 49ers Player Props
|Quarterback||Completions||Passing Yards||Passing TD|
|Josh Allen (BUF)||23.5 (Ov -106 | Un -118)||269.5 (Ov -112 | Un -112)||1.5 (Ov -143 | Un +115)|
|Nick Mullens (SF)||22.5 (Ov -112 | Un -112)||250.5 (Ov -112 | Un -112)||1.5 (Ov -125 | Un +101)|
|Running Backs||Attempts||Rush Yards||Rush + Receiving Yards|
|Devin Singletary (BUF)||8.5 (Ov -140 | Un +100)||36.5 (Ov -112 | Un -112)||52.5 (Ov -112 | Un -112)|
|Zack Moss (BUF)||9.5 (Ov +100 | Un -140)||34.5 (Ov -112 | Un -112)||44.5 (Ov -112 | Un -112)|
|Raheem Mostert (SF)||12.5 (Ov -112 | Un -112)||53.5 (Ov -112 | Un -112)||65.5 (Ov -112 | Un -112)|
|Wide Receivers + Tight Ends||Receptions||Receiving Yards||Longest Reception|
|Stefon Diggs (BUF)||6.5 (Ov +125 | Un -157)||77.5 (Ov -112 | Un -112)||24.5 (Ov -112 | Un -112)|
|Cole Beasley (BUF)||4.5 (Ov -143 | Un +115)||56.5 (Ov -112 | Un -112)||21.5 (Ov -112 | Un -112)|
|Gabriel Davis (BUF)||3.5 (Ov +125 | Un -157)||41.5 (Ov -112 | Un -112)||20.5 (Ov -112 | Un -112)|
|Deebo Samuel (SF)||5.5 (Ov +125 | Un -157)||48.5 (Ov -155 | Un +125)||18.5 (Ov -112 | Un -112)|
|Brandon Aiyuk (SF)||4.5 (Ov +134 | Un -167)||51.5 (Ov -112 | Un -112)||21.5 (Ov -112 | Un -112)|
|Kendrick Bourne (SF)||2.5 (Ov -112 | Un -112)||30.5 (Ov +100 | Un -124)||16.5 (Ov -112 | Un -112)|
|Dawson Knox (BUF)||1.5 (Ov -143 | Un +115)||15.5 (Ov -112 | Un -112)||11.5 (Ov -112 | Un -112)|
|Jordan Reed (SF)||3.5 (Ov +115 | Un -143)||35.5 (Ov -112 | Un -112)||17.5 (Ov -112 | Un -112)|
Game Preview and Betting Angles
The 49ers need a win to keep pace in the NFC playoff hunt. The last Wild Card spot is up for grabs, but Buffalo is no easy customer. The Bills took their momentum from the 2019 season and carried that right into 2020. Let’s dive into the nitty-gritty details on both of these teams as they prepare for this Monday Night Football clash.
49ers Game Notes
The 49ers have faced their fair share of adversity this year. After winning the NFC last year and nearly edging out the Kansas City Chiefs in the Super Bowl, San Francisco has had to deal with a rash of injuries to key guys like Nick Bosa and Jimmy Garoppolo. And now the 49ers are forced to move their home field to Arizona due to COVID-19 restrictions.
But despite all these challenges, San Francisco has a legitimate shot at making the playoffs. The Los Angeles Rams were cruising into Week 12, but the Niners were able to beat LA on a last-second field goal. Wide receiver Deebo Samuel’s 133 yards helped this banged-up offense move the ball enough to put up points on the board. Samuel has dealt with his own injuries this year, but he should be good to go on Monday night.
San Francisco’s defense excels against the pass. They rank fourth in the NFL in passing yards allowed with 206.5 yards per game. The return of Richard Sherman helped provide a lift to that defense against the Rams. The five-time All-Pro had seven tackles and an interception in his return.
Bills Game Notes
Third-year quarterback Josh Allen is taking a major leap forward this year. Although the hype has died down in recent weeks, Allen received some well-deserved early MVP consideration. The Wyoming product needs to be a little more consistent, but he’s been mostly good. Cutting down on costly turnovers is a must for Allen.
It’s clear that one major reason for Allen’s continued improvement is the recent addition of wide receiver Stefon Diggs. The former fifth-round pick already has 80 receptions, 945 yards, and four touchdowns this season. He’s opening up the offense for other guys like Gabriel Davis, John Brown, and Cole Beasley to flourish.
Buffalo’s two-headed rushing attack of Devin Singletary and Zack Moss helps keep the offense balanced, but San Francisco’s staunch run defense should be difficult to penetrate. The 49ers rank top 10 in the NFL in yards per carry (4.0) and yards per game (108.7).
How To Watch 49ers – Bills
- Date: Monday, Dec. 7
- Time: 8:15 p.m. ET
- Location: State Farm Stadium (Glendale, Arizona)
- TV: ESPN
Betting Picks and Score Prediction
These are two teams with a ton to play for on Monday Night Football. The Bills are trying to hold onto their AFC East lead and secure a home game in the playoffs. The 49ers are looking to stay in the playoff hunt in the NFC despite tons of injuries and adversity this year. Look for a high-scoring game and take the over on the total points.