Last Updated on May 20, 2021


When it comes to legal sports betting, it is always football season. Whether the NFL or college football, bettors are always placing wagers on football. The Week 1 opening lines for some top college football matchups were released, and bettors are already hammering the opening lines as college football notoriously is a market that bettors look to exploit.

With DraftKings Sportsbook releasing odds for Week 1 of the college football season, let’s take a look at those opening odds and prices along with our early betting picks for the marquee games.


Week 1 College Football Lines

There are quite a few marquee matchups in Week 1 of the college football season this year, let’s take a look at the opening point spreads and moneylines for some Week 1 college football contests, odds courtesy of DraftKings Sportsbook.


UNC vs. Virginia Tech Week 1

Team Spread Moneyline
UNC -6.5 -230
Virginia Tech +6.5 +180


Georgia vs. Clemson Week 1

Team Spread Moneyline
Georgia +4 +145
Clemson -4 -182



Penn State vs. Wisconsin Week 1 

Team Spread Moneyline
Penn State +3.5 +123
Wisconsin -3.5 -155


Alabama vs. Miami Week 1

Team Spread Moneyline
Alabama -17.5 -1000
Miami +17.5 +575


LSU vs. UCLA Week 1

Team Spread Moneyline
LSU -4.5 -200
UCLA +4.5 +155


Notre Dame vs. Florida State Week 1

Team Spread Moneyline
Notre Dame -9.5 -400
Florida State +9.5 +285



Some Early Week 1 Picks…..

With these six games having their odds released for Week 1 of the CFB season, there is some value to be had on both the spreads and moneylines. Here are our early betting picks for Week 1.


UNC vs. Virginia Tech

  • UNC (-6.5)
  • UNC ML (-230)

UNC may have lost a lot of their skill players, but they return one of the best quarterbacks in the country and are set to see massive odds movement as the season approaches.


Georgia vs. Clemson

  • Clemson (-4)
  • Clemson ML (-182)

Clemson lost Trevor Lawrence and Travis Etienne to the NFL, but return some of the better recruiting classes in college football from the last few seasons. The Tigers continue to reload, and the next quarterback ready to go from Clemson to the NFL is DJ Uiagalelei, whose skills will be on-hand for Week 1. Clemson at home would be closer to 7-point favorites, but this game in a neutral site makes it -4. Keep in mind that Charlotte is a short drive from Clemson, SC though.


Penn State vs. Wisconsin

  • PSU (+3.5)
  • PSU ML (+123)

The spread (+3.5) is a better value than the moneyline at the moment, as this is expected to be a close one. It will be interesting to see how Penn State bounces back in 2021.


Alabama vs. Miami

  • Alabama (-17.5)

The Crimson Tide moneyline is -1000, which is a ton of juice so taking the spread is the play here despite a very high number. With that said, Alabama is likely to be favored by more than three touchdowns by Week 1, so you will get plenty of value here. Yes, Alabama lost Mac Jones, Najee Harris, Jaylen Waddle, DeVonta Smith and others. No, it does not matter.


LSU vs. UCLA Week 1

  • LSU (-4.5)

This line has already moved, as it opened at -1.5 right away at FanDuel, then was taken off the board. Expect it close closer to a touchdown by the time Week 1 comes around.


[metabet_core_odds_board league=”ncaaf” site_id=”actionrush”  hide_consensus=”yes”]


Bet on College Football at DraftKings Sportsbook

College football, like the NFL, is a year-round sport when it comes to betting. You can wager on futures, awards, player props, and even the Week 1 odds as they are released early. Here is a look at some college football betting markets you can wager on, with our odds and picks as well.



DraftKings Sportsbook App is the most popular in the country!

New users get a $1,050 bonus!

Contact me