Last Updated on September 22, 2020

  • One of the biggest spreads of Week 4 features LSU vs. Mississippi State on Saturday, Sept. 26th, at 3:30 pm ET at Tiger Stadium
  • LSU is currently -17 point favorites over Miss. State in the SEC opener for both teams
  • Find the latest betting odds, a preview of the matchup and a pick for the game in the article below


SEC football is back this weekend and LSU is starting things off with Mississippi State. The defending national champs are going to look like a different team this year without Joe Burrow under center, but they are still opening the season as heavy favorites against the Bulldogs.

With coronavirus changing everything about the 2020 college football season, the SEC is moving forward with an all-conference schedule. It makes sense given the travel concerns and it shouldn’t hurt any SEC team’s chances of making the College Football Playoff.

If you win the SEC, you are going to have a chance to win the National Championship. LSU is currently 10th in odds to win it all and fourth to win the SEC championship.


LSU – Mississippi State Betting Odds

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The Tigers are currently 16.5-point favorites, but you can snag the Bulldogs as 17-point underdogs on some sportsbooks. Either way, this is projected to be around a three-score game with LSU dominating. Mississippi State will have to travel to Death Valley in Baton Rouge, LA for their season opener, but the stadium will only have about 26,000 fans (25% capacity).

The total points are set to 57 on some sportsbooks and 57.5 on others. It’s tough to know what to expect from both offenses in the first game of the season.


Game Preview & Betting Angles 

LSU is expected to be one of the powerhouses in the SEC again. As previously mentioned, Heisman winner Joe Burrow is playing on Sundays in the NFL now, but head coach Ed Orgeron expects Myles Brennan to come in and do well as Burrow’s successor. Although it’s unwise to expect him to replicate Burrow’s numbers from last season, Brennan is going to have a strong defense and playmakers around him.

Mississippi State is coming off of a disappointing 6-7 season in which they fired their head coach, Joe Moorhead, and replaced him with the always entertaining Mike Leach. Expect Mississippi State to come out firing in 2020 with Leach’s “Air Raid” offense, but it won’t be easy to throw the ball all over LSU’s defense.

Leach is going to have a highly-touted prospect throwing the ball this season though. K.J. Costello is coming over from Stanford and he is expected to be a future NFL Draft pick. Leach knows Costello well from his time as head coach at Washington State. He obviously knows that the 6-foot-5 quarterback has a cannon for an arm and can do big things given the right opportunity.

Costello only played in five games last year due to injuries and if he can stay healthy, he’ll give Leach a big, strong arm to work with. In 2018, he threw for 3,540 yards, 29 touchdowns, and just 11 interceptions. With Leach’s major emphasis on throwing the ball, we can expect Costello to have plenty of opportunities to throw the ball down the field this season.



Historical Matchup Stats

LSU holds a significant advantage in the historical matchup over Mississippi State. The Tigers are 73-35-3 all-time against the Bulldogs. In last year’s meeting, LSU dominated with a 36-13 victory in Starkville, MS.

The last time Mississippi State beat LSU was in 2017, but since the year 2000, the Bulldogs only have two wins against their SEC West rival. This has long been a one-sided rivalry with LSU holding the major edge.


How To Watch LSU vs. Mississippi State

LSU – Mississippi State is getting a spot in primetime on CBS for the 3:30 p.m. ET game. This is the slot reserved for the biggest SEC game of the week and it should come as no surprise that the defending national champions are going to be front and center. Sure, they are losing a ton of the big names that brought them the title, but LSU is always going to be a big draw in the SEC and nationally.

Brad Nessler is the lead play-by-play man for CBS with Gary Danielson serving as the color commentator. Jamie Erdahl will handle sideline reporter duties.


Betting Picks & Score Prediction

LSU is going to have a bunch of new faces, but despite the significant roster turnover, they have continuity on the coaching staff. Orgeron already established a culture in Baton Rouge and his offensive coordinator, Steve Ensminger, is back again in 2020. Passing game coordinator Joe Brady left for an offensive coordinator job in the NFL, but he’s replaced by long-time coach Scott Linehan.

Mike Leach is a heck of a coach, but he’s looking to implement his offense on a brand new team with a brand new quarterback. There’s a lot to like about Mississippi State’s future, but it’s tough to see them jumping out to a hot start in 2020. For this reason, we’re taking LSU -16.5. Even with the diminished home crowd, playing in Death Valley is another big advantage for the Tigers.


Final Score Prediction: LSU wins 38-14

Small’s 2020 CFB Record: 0-2