NFL Upset Picks




Everyone loves an underdog. When it comes to betting on the NFL, underdogs have a chance to make bettors more money, but are less likely to win on the moneyline of course.

While there are not many two-or-more touchdown underdogs throughout the NFL season, there are always upsets on a week-to-week basis where teams that are favored lose games. Finding this value is a great way to potentially become a more profitable bettor in the long run.

Below, let’s take a look at the latest odds for Week 6 in the NFL, our favorite upset picks, and more. In addition, you can find out who the public is betting on for this week in the NFL.



Upset Picks for Week 6 in the NFL

Whether against the spread or on the moneyline, there are a number of upsets every week in the NFL. While we do not see as many large spreads as we do in college football, there is always a handful of upsets in the NFL that can swing a week for bettors. Finding the best value is key in the NFL, with legal sportsbooks varying by price. While upset picks on the moneyline are less likely to happen, the payout is much greater. This is where the phrase “any given Sunday” comes into play, where the NFL is so close (relative to college football) in terms of talent disparity. This makes betting on underdogs and upsets much more fun. In Week 5, we saw the Bills flatten the Kansas City Chiefs in an upset, and only one unbeaten team remains in the Arizona Cardinals, who are underdogs in Week 6.

Without further ado, here is a list of our favorite upset picks for Week 6 in the NFL, and their prices at the time of the pick.

  • Arizona Cardinals +130 vs. Clevelend Browns at DraftKings Sportsbook
  • Jacksonville Jaguars +170 vs. Miami Dolphins at DraftKings Sportsbook
  • Las Vegas Raiders +170 vs. Denver Broncos at Caesars Sportsbook

If you are looking to see who the public is betting on in these NFL games, take a look here.


Latest NFL Week 6 Odds

When betting on upset picks, one of the keys to being a more successful bettor is finding the best line on your underdog. In order to do that, you have to shop for the best odds in your state. Below, you will find the best odds on every NFL game across multiple legal sportsbooks in your state. For example, if you like the New York Jets at +4.5, but you can get them at +5.5 on another legal sportsbook, be sure to take the extra point to increase your chances of winning.

Let’s take a look at the spreads for each NFL game this week, finding the best prices for your NFL upset picks.


NFL Week 6 Betting Splits

One of the most important aspects of betting information is learning who the public is on. We track NFL public betting and consensus picks, and it will help you make betting decisions. For Week 6 in the NFL, here is a look at the latest public betting information. Below, you can see just how much money (and tickets) are on the spread, moneyline, and totals for each NFL game when the information is provided.

All consensus betting information is courtesy of DraftKings Sportsbook.


Who are the biggest underdogs this week in the NFL?

For Week 6 in the NFL, there is just one double-digit underdog in the Giants vs. the Rams. However, there are a handful of teams that are dogs by at least a touchdown, making this a fun one for bettors. Here are a list of the top underdogs for Week 6 in the NFL, who would be huge upsets given the point spread.

  • New York Giants +10.5 vs. Los Angeles Rams
  • Houston Texans +10 vs. Indianapolis Colts
  • Philadelphia Eagles +7 vs. Tampa Bay Buccaneers
  • Washington Football Team +6.5 vs. Kansas City Chiefs
  • Tennessee Titans +5.5 vs. Buffalo Bills


More NFL Betting Info

Want more NFL betting information?

Looking for college football upset picks? Check out the latest, here.


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