Last Updated on April 12, 2021



The spring brings a plethora of wagering possibilities, and after the Masters and MLB opening day, the next big event is the Kentucky Derby. This year will be the 147th running of the Kentucky Derby, and with the event taking place on May 1st, the odds are beginning to solidify. After the “Road to the Kentucky Derby” races, TwinSpires’ Ed DeRosa has released what he believes will be the odds for the morning line of the Derby.

With the Kentucky Derby a few weeks away, TwinSpires’ handicapper has predicted who he believes will be the favorite, along with other odds. Let’s take a look at the latest for the 147th Kentucky Derby.


2021 Kentucky Derby Odds – TwinSpires

After the Road to the Kentucky Derby races, TwinSpires’ Ed DeRosa has released his expected odds for the morning line of the Derby. Here is a look at the first 18 horses, all at +4000 or better to win the Kentucky Derby.

Horse TwinSpires Opening Odds to Win Kentucky Derby
Essential Quality +350
Hot Rod Charlie +800
Rock Your World +800
Highly Motivated +800
Known Agenda +1200
Concert Tour +1200
Super Stock +1400
Media Spirit +1800
Midnight Bourbon +2000
Mandaloun +2000
Like The King +3000
Bourbonic +3000
Soup and Sandwich +3000
Dynamic One +3000
Caddo River +3000
Helium +4000
Crowded Trade +4000
Sainthood +4000


As you can see, DeRosa has Essential Quality listed as the clear favorite. He was quoted as to why:

“After Concert Tour’s disappointing 3rd in the Arkansas Derby, there is now no doubt in my mind that undefeated champion Essential Quality will start the Derby a well-supported favorite…The combination of his unblemished record, fast times, local trainer and color (grey) will all add up to a large amount of public support.” said DeRosa

After Essential Quality, Hot Rod Charlie, Rock Your World, and Highly Motivated come in at +800 before a drop-off to +1200 for Known Agenda and Concert Tour. This will certainly be a race to remember, but keep an eye on the odds.


Ed DeRosa Predicts Essential Quality to be Derby Favorite

DeRosa is the handicapper for TwinSpires, and he has released his likely morning line odds. The odds are listed above, but he mentions that the clear-cut favorite is Essential Quality. Here is why.


One of the notable quotes from DeRosa about Essential Quality and this year’s Derby was as follows:

“Choosing the favorite is easy, but finding a clear second pick is more difficult with a bunch of contenders all looking to go off around the 8/1 to 10/1 range.”

From a betting perspective, that seems that DeRosa is keen on Essential Quality being the clear favorite and the questions being around the horse that will have the second-best odds at post time.


Can You bet the Kentucky Derby Online?

Betting on the Kentucky Derby is a tradition as old as time, or precisely 147 years old this year. Betting on horse racing is far more widespread than sports betting, and there are plenty of betting apps to use in order to wager on the Kentucky Derby. You can bet in a bunch of different ways, including horses to win, place, show, exactas, and more.

Here are two of our favorite horse racing betting apps:

  • TwinSpires
  • TVG



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Bet online or via mobile app.

Action Rush Staff