Last Updated on March 18, 2021

With the new format of the NCAA Tournament in the last few seasons, there was an added pool of four teams to the bracket. These games are called the “First Four”, and allows for some bubble teams to earn a shot to reach the first round of the tournament. One of this year’s play-in games was Wichita State against Drake, and Drake pulled out a close victory to advance to the first round and face USC.

Let’s take a look at the odds, betting picks, and more for the matchup between Drake and USC as the 6/11 matchup in the first round of the NCAA Tournament, as March Madness begins.



Drake wins First Round, USC Next

After a thrilling victory in the “First Four”, Drake will face off against USC in the first round.

Where: Bankers Life Fieldhouse, Indianapolis
When: Saturday, March 20, 2021 at 4:30 PM EST
Watch: TNT, March Madness App

Drake pulled out a close win over Wichita State to open up the tournament, and they will move on to face USC in the official “first round” of the NCAA Tournament. Drake will officially be the 11th seed, and they will take on the sixth seed USC Trojans, as Drake looks for their first official tournament win in 50 years.

Check out these seven best promotions for this year’s NCAA tournament at various betting platforms.


USC vs. Drake Odds

Here’s a look at the opening odds for USC against Drake, courtesy of William Hill Sportsbook.

Team Spread Moneyline Total
USC -6.5 -290 o139
Drake +6.5 +245 u139

USC is favored by 6.5 points, which is not surprising given the talent differential and how poorly Drake shot in the First Four. It will be tough sledding for Drake, but it is the NCAA Tournament, and anything can happen.

Bet on USC and Drake now at William Hill Sportsbook.

Keep track of who is the public is betting on for the tournament to gain an edge.

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NCAA Tournament 2021 Picks – USC vs. Drake

The odds have been released for Drake vs. USC, and here are our betting picks for the spread, the total, and moneyline. After a close win against Wichita State, Drake will need to shoot much better to defeat the Trojans of USC.

USC vs. Drake Picks

Odds courtesy of William Hill.

  • USC -6.5
  • USC -290
  • Under 139

USC is far more talented, and with Drake’s struggle to score the basketball against Wichita State, it makes for a lopsided matchup in USC’s favorite. Be sure to bet these before the spread rises, at William Hill Sportsbook.

Want more picks? We broke down the Wisconsin and North Carolina matchup, here.



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